Developer Sik recently proposed an interesting idea: Why not make a USB adapter that allows a modern computer mouse to be used in place of the Sega Mouse for the Genesis / Mega Drive. Sik wanted to take it one step further and also include the correct information so the wheel on modern mice can be utilized as well.
Older “ball” mice like Sega used wear out quickly and aren’t very accurate. Also, the original Sega Mouse is climbing in price, so having a modern solution seems like a great option. If you have the ability to contribute to this project, please check out the thread: https://gendev.spritesmind.net/forum/viewtopic.php?f=23&t=3068